Angiotensin-Converting Enzyme Inhibitors Reduce Mortality in Hypertension: A Meta-Analysis of Randomized Clinical Trials of Renin–Angiotensin–Aldosterone System Inhibitors Involving 158,998 Patients

Study Questions:

What are the effects of renin–angiotensin–aldosterone system (RAAS) inhibitors as a class of drugs, as well as of angiotensin-converting enzyme (ACE) inhibitors and AT1 receptor blockers (ARBs) separately, on all-cause mortality in hypertensive patients?