Thrombolytic Therapy for the Treatment of Prosthetic Heart Valve Thrombosis in Pregnancy With Low-Dose, Slow Infusion of Tissue-Type Plasminogen Activator

Study Questions:

What are the safety and efficacy of low-dose (25 mg), slow infusion (6 hours) tissue-type plasminogen activator (tPA) for the treatment of prosthetic heart valve (PHV) thrombosis in pregnant women?