Should Patients With Acute Coronary Disease Be Stratified for Management According to Their Risk? Derivation, External Validation, and Outcomes Using the Updated GRACE Risk Score

Study Questions:

What is the performance of a simplified Global Registry of Acute Coronary Events (GRACE) risk predictor (GRACE score 2.0), which incorporates substitutions for creatinine and Killip class, and which incorporates testing for nonlinear associations between outcomes and continuous variables?