Thrombolysis for Pulmonary Embolism and Risk of All-Cause Mortality, Major Bleeding, and Intracranial Hemorrhage: A Meta-Analysis

Study Questions:

What are the mortality benefits and bleeding risks associated with thrombolytic therapy compared with anticoagulation in acute pulmonary embolism (PE), including the subset of hemodynamically stable patients with right ventricular (RV) dysfunction (intermediate-risk PE)?