Chronic Vagal Stimulation for the Treatment of Low Ejection Fraction Heart Failure: Results of the NEural Cardiac TherApy foR Heart Failure (NECTAR-HF) Randomized Controlled Trial

Study Questions:

Does a single dose of vagal nerve stimulation (VNS) attenuate cardiac remodeling, improve cardiac function, and increase exercise capacity in symptomatic heart failure (HF) patients with severe left ventricular (LV) systolic dysfunction despite guideline-recommended medical therapy?