Late Breaking Clinical Trials

** Denotes trials that will have an ACC News Conference

SUNDAY, MARCH 18, 2001

Late-Breaking Trials in Interventional Cardiology (#22), Hall E
Co-chairs: Spencer B. King, III, MD, and Eric J. Topol, MD

8:45 a.m.
**Restenosis Intra-Stent: Balloon Angioplasty vs. Elective Stenting: Results of a Randomized Trial—Fernando Alfonso, MD, of Madrid, Spain

8:58 a.m.
**The Beta-Cath System Trial—Richard E. Kuntz, MD, of Boston

9:10 a.m.
Direct Myocardial Laser Revascularization Using Biosense Left Ventricular Electromechanical Mapping: Final Results of the DIRECT Randomized Trial—Martin B. Leon, MD, of New York City

9:22 a.m.
**The Stent or Surgery Trial (SoS)—Rodney Stables, MD, of Liverpool, United Kingdom

9:34 a.m.
**The Medicine, Angioplasty, or Surgery Study (MASS II): A Randomized, Controlled Clinical Trial of Medical Therapy, Coronary Angioplasty, or Bypass Surgery for Multivessel Coronary Artery Disease—Whady Hueb, MD, of Sao Paulo, Brazil

9:46 a.m.
**The Washington Radiation for In-Stent Restenosis Trial for Saphenous Vein Grafts (SVG WRIST)—Ron Waksman, MD, of Washington, D.C.

SUNDAY, MARCH 18, 2001

Arrhythmia/Device Trial Update (#61), Hall A3
Co-chairs: Gerald V. Naccarelli, MD, and Mark H. Schoenfeld, MD

8:00 a.m.
Prophylactic Use of Implantable Cardioverter Defibrillators in Patients With Idiopathic Dilated Cardiomyopathy: The Cardiomyopathy Pilot Trial (CAT)—Seven-Year Follow-up—Karl-Heinz Kuck, MD, of Hamburg, Germany

8:25 a.m.
Update on Pacing Trials—Gervasio A. Lamas, MD, of Miami Lakes, Fla.

8:50 a.m.
Sudden Cardiac Death: Primary and Secondary Prevention Trial Update—David S. Cannom, MD, of Los Angeles

9:15 a.m.
**Dual-Site Atrial Pacing for Prevention of Atrial Fibrillation Trial (DAPPAF)—Sanjeev Saksena, MD, of Millburn, N.J.

9:40 a.m.
Update on Atrial Fibrillation Trials—D. George Wyse, MD, of Calgary, Canada


MONDAY, MARCH 19, 2001

Late-Breaking Clinical Trials I (#405), Hall E
Co-chairs: Jeffrey L. Anderson, MD, and Sanjiv Kaul, MD

9:15 a.m.
Aggressive Diagnosis of Restenosis (ADORE) Trial—Mark J. Eisenberg, MD, of Montreal, Canada

9:30 a.m.
**Adenovirus FGF Angiogenic Gene Therapy (AGENT) Trial for Stable Angina—Cindy L. Grines, MD, of Royal Oak, Mich.

9:45 a.m.
**Therapeutic Angiogenesis With Recombinant Fibroblast Growth Factor-2 for Intermittent Claudication (TRAFFIC): Results After 180 Days—Robert J. Lederman, MD, of Bethesda, Md.

10:00 a.m.
A Placebo-Controlled Safety and Pharmacology Study of ALT-711 in Older Patients With Stiffened Cardiovasculature—David A. Kass, MD, of Baltimore, Md.

10:15 a.m.
**Clopidogrel in Unstable Angina to Prevent Recurrent Ischemic Events (CURE)—Salim Yusuf, MD, of Ontario, Canada


TUESDAY, MARCH 20, 2001

Late-Breaking Clinical Trials II (#414), Hall E
Co-chairs: Barry M. Massie, MD, and John M. Miller, MD

8:30 a.m.
Mortality and Stroke Rates in a Trial of Rhythm Control vs. Rate Control in Atrial Fibrillation: Results from the STAF Pilot Phase (Strategies of Treatment of Atrial Fibrillation)—Joerg Carlsson, MD, Detmold, Germany

8:45 a.m.
**Multicenter InSync Randomized Clinical Evaluation (MIRACLE): Results of a Randomized, Double-Blind, Controlled Trial to Assess Cardiac Resynchronization Therapy in Heart Failure Patients—William T. Abraham, MD, of Lexington, Ky.

9:00 a.m.
**Carvedilol Prospective Randomized Cumulative Survival Trial (COPERNICUS)—Milton Packer, MD, of New York City

9:15 a.m.
**Carvedilol Post-Infarct Survival Control in Left Ventricular Dysfunction (CAPRICORN)—Henry J. Dargie, MD, of Glasgow, United Kingdom

9:30 a.m.
**Prospective, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of the Efficacy and Safety of Tezosentan in Patients With Acute Decompensated Heart Failure (RITZ-2)—Guillermo Torre-Amione, MD, of Houston

9:45 a.m.
Better Long-Term Clinical and Angiographic Results After Stent Placement for Long Coronary Artery Stenoses Guided by Intravascular Ultrasound Compared to Angiography: Results of a Randomized Study—Pranobe Oemrawsingh, MD, of Leiden, the Netherlands


WEDNESDAY, MARCH 21, 2001

Late-Breaking Clinical Trials III (#423), Hall E
Co-chairs: Joseph E. Parrillo, MD, and Eric S. Williams, MD

8:30 a.m.
**Multiple Outcomes of Raloxifene Evaluation (MORE)—Elizabeth Barrett-Connor, MD, of La Jolla, Calif.

8:45 a.m.
Improved Reperfusion and Clinical Outcome With Enoxaparin as an Adjunct to Streptokinase Trombolysis in Acute Myocardial Infarction (AMI-SK)—Angeles Alonso, MD, Madrid, Spain

9:00 a.m.
**The Pravastatin Inflammation/CRP Evaluation (PRINCE)—Paul M. Ridker, MD, of Boston

9:15 a.m.
**Treat Angina With Aggrastat and Determine Cost of Therapy With an Invasive or Conservative Strategy (TACTICS)-TIMI 18—William S. Weintraub, MD, of Atlanta

9:30 a.m.
**Program to Assess Alternative Treatment Strategies to Achieve Cardiac Health (PATCH): EDTA Study—D. George Wyse, MD, of Calgary, Canada

9:45 a.m.
Effects of Enrasentan, a Nonselective Endothelin Receptor Angagonist, in Class II-III Heart Failure: Results of the ENCOR Trial—William T. Abraham, MD, of Lexington, Ky.

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