Genetics can establish a baseline lifelong trajectory for cardiovascular disease risk for everyone. Learn the latest about testing, actionability, and limitations as well as future directions.

In this interview, Pradeep Natarajan, MD, MMSc and Steven E. Nissen, MD, MACC, with Manuel Rivera Maza, MD, discuss "When Is Genetic Testing Helpful?"

Related References:

1. Aragam KG, Dobbyn A, Judy R, et al. Limitations of Contemporary Guidelines for Managing Patients at High Genetic Risk of Coronary Artery Disease. J Am Coll Cardiol 2020;75:2769-2780.
2. Aragam KG, Natarajan P. Polygenic Scores to Assess Atherosclerotic Cardiovascular Disease Risk: Clinical Perspectives and Basic Implications. Circ Res 2020;126:1159-1177.
3. Natarajan P, Young R, et al. Polygenic Risk Score Identifies Subgroup With Higher Burden of Atherosclerosis and Greater Relative Benefit From Statin Therapy in the Primary Prevention Setting. Circulation 2017;135:2091-2101.

Clinical Topics: Prevention

Keywords: ACCELLite, Genetic Testing

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