ACCEL Lite: Chronic Thromboembolic Pulmonary Hypertension (CTEPH): Procedures or Pills?

Apr 08, 2025   |  Shashank S. Sinha, MD, FACC; Anjali Vaidya, MD, FACC

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Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare and potentially fatal form of elevated blood pressure in the lungs. CTEPH treatment overall is a very complex clinical assessment and medical decision. Treatment options may include pulmonary thromboendarterectomy (PTE) surgery, balloon pulmonary angioplasty (BPA), or medical therapy.

In this interview, Drs. Shashank Sinha and Anjali Vaidya discuss how to approach the treatment decision for CTEPH once a diagnosis has been made.

Related References:

  1. Jais X, Brenot P, Bouvaist H, et al. Balloon pulmonary angioplasty versus riociguat for the treatment of inoperable chronic thromboembolic pulmonary hypertension (RACE): a multicenter, phase 3, open-label, randomized controlled trial and ancillary follow-up study. Lancet Respir Med 2022;10:961-71.
  2. Lang IM, Andreassen AK, Andersen A, et al. Balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension: a clinical consensus statement of the ESC working group on pulmonary circulation and right ventricular function. Eur Heart J 2023;44:2659-71.
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Clinical Topics: Diabetes and Cardiometabolic Disease, Heart Failure and Cardiomyopathies, Prevention, Pulmonary Hypertension and Venous Thromboembolism, Vascular Medicine, Pulmonary Hypertension, Hypertension, Invasive Cardiovascular Angiography and Intervention

Keywords: ACCELLite, Hypertension, Pulmonary, AHA24