The newest issue of JACC: Case Reports features the second part in a procedural complications series, as well as four mini-focus issues spotlighting recent hypertrophic cardiomyopathy guideline cases, imaging, electrophysiology and chest wounds. In the Guest Editor's Page, "2021: The Light at the End of the Tunnel?," Sarah M. Birkhoelzer, MD; Editor-in-Chief Julia Grapsa, MD, PhD, FACC; and Mary Norine Walsh, MD, MACC, reflect on 2020 and discuss moving forward in 2021. Published with the issue are three video case reviews on procedural complications, structural complications and pressure-volume loops. Read the entire issue, listen to issue podcasts and subscribe to JACC Journals email alerts.