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WASHINGTON (Feb 28, 2018) -
Football players show structural changes in the heart and face an elevated risk of heart rhythm disorders later in life, according to research presented at the American College of Cardiology’s 67th Annual Scientific Session.
In one study, former professional NFL players were found to be more than five times as likely to have a heart rhythm disorder, such as atrial fibrillation (AFib), compared with the general public. While previous studies have shown similarly increased rates of AFib among endurance athletes such as long-distance runners, this is the first study to find an association for athletes in a strength-based sport.
In a separate study, freshman collegiate football players showed significant structural changes to the heart, including enlargement of the aortic root after just one season of play. The increased size of the aortic root is a new finding and one for which the clinical significance remains unclear.
“We know that sporting activity increases longevity and has multiple benefits for the cardiovascular system, but our findings seem to suggest that perhaps when you get to the extreme ends that we see in these elite athletes, there may be a negative impact on the heart,” said Dermot Phelan, MD, PhD, and director of the sports cardiology center at Cleveland Clinic, who led the study focused on former NFL players. “Players should not assume that leading a healthy lifestyle in terms of regular exercise means that they’re immune from developing cardiac problems and, in fact, they may be at higher risk for things like atrial fibrillation.”
Phelan and colleagues conducted a cardiovascular screening of 460 former NFL players that included an electrocardiogram, echocardiogram, blood tests and a cardiovascular history questionnaire. They compared the results to a sample of 925 people from the general public with similar demographics to the NFL cohort in terms of age and race.
After controlling for blood pressure, body mass index, age and race, researchers found NFL players had a 5.5-times higher likelihood of AFib compared with non-athletes, as well as other signs of abnormal electrical impulses in the heart. The football players also tended to have a lower resting heart rate than their non-athlete counterparts, which is usually indicative of cardiovascular health but in the athletes’ cases, this may have masked the symptoms of AFib.
“Because they had a low resting heart rate, most of them did not get the rapid heart rate that typically warns people that they have atrial fibrillation,” Phelan said. “Most were unaware of it until our screening study. The message is that they need to get regular checkups to be sure they are maintaining a proper heart rhythm.”
AFib is known to cause heart palpitations, dizziness and chest pain and increases the risk of stroke, heart attack and heart failure. Phelan and colleagues did not assess these impacts of AFib in their study.
For the study of college football players, researchers at Emory University performed two cardiovascular tests, echocardiography and vascular applanation tonometry (a study tool that measures vascular function and arterial stiffness), both before and after a complete college football season, in 136 freshman football players and 44 college freshmen who did not play football.
After the football season, all study participants had gained weight, but only the football players showed significant enlargement of the aortic root (the place where the aorta meets the heart). The study is the first to assess longitudinal changes in the aortic root size in conjunction with changes in cardiac structure and function associated with college football participation. Although the athletes’ aortic roots were still within the normal range, enlargement of the aortic root may not completely be a consequence of exercise training, researchers said.
The study results also demonstrated findings observed in previous studies, namely that the football players, particularly the larger lineman position players, tended to develop higher systolic blood pressure, increases in vascular stiffening and thickening of the left ventricle, changes that may be beyond those observed after normal intense exercise training.
“We often think of football players, like all athletes, as the picture of health, but we’re gaining this body of knowledge that signals some maladaptive cardiovascular changes and potentially even early cardiac risk in some of these players,” said Jonathan Kim, MD, primary study author, chief of sports cardiology, assistant professor of medicine at Emory University and lead cardiologist for the Atlanta Falcons. “It suggests we need to pay close attention to the heart health of young football players. Also, future studies will need to focus on understanding the clinical significance of our findings.”
Kim cautioned that it remains unclear whether the observed changes are detrimental to players’ health and noted there are many factors that are part of the football experience that could contribute to the differences observed in the study.
Both Phelan and Kim said more research is needed to elucidate the underlying mechanisms involved in the outcomes observed in their studies and to determine how their results relate to outcomes seen in other groups of athletes. They underscored the need for football players of all ages to get regular medical checkups to identify any early signs of cardiovascular disease.
Kim’s research was supported by the National Institutes of Health.
Aagaard will present the study, “Risk of Arrhythmia and Conduction Disease in Former National Football League Players,” on Monday, March 12 at 1:00 p.m. ET in Arrhythmias and Clinical EP Moderated Poster Theater, Poster Hall A/B.
Jonathan Kim and Keyur Patel will present the study, “Aortic Root Dilatation Associated with Collegiate American Style Football Participation,” on Saturday, March 10 at 10:00 a.m. ET in Poster Hall A/B.
The ACC’s Annual Scientific Session, which will take place March 10-12 in Orlando, brings together cardiologists and cardiovascular specialists from around the world to share the newest discoveries in treatment and prevention. Follow @ACCinTouch, @ACCMediaCenter and #ACC18 for the latest news from the meeting.
The American College of Cardiology is a 52,000-member medical society that is the professional home for the entire cardiovascular care team. The mission of the College is to transform cardiovascular care and to improve heart health. The ACC leads in the formation of health policy, standards and guidelines. The College operates national registries to measure and improve care, offers cardiovascular accreditation to hospitals and institutions, provides professional medical education, disseminates cardiovascular research and bestows credentials upon cardiovascular specialists who meet stringent qualifications.