EXpansion of Stents After Intravascular lithoTripsy Versus Conventional Predilatation in CALCified Coronary Arteries - EXIT-CALC

Sep 26, 2022
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Author/Summarized by Author:
Anthony A. Bavry, MD, MPH, FACC
Summary Reviewer:
Deepak L. Bhatt, MD, MPH, MBA, FACC
Date Presented:
09/19/2022
Date Updated:
09/26/2022
Original Posted Date:
09/26/2022
References

Contribution To Literature:

The EXIT-CALC trial failed to show that intravascular lithotripsy improves stent expansion in calcified coronary arteries.

Description:

The goal of the trial was to evaluate intravascular lithotripsy compared with balloon angioplasty among patients with severe coronary artery calcium undergoing percutaneous coronary intervention (PCI).

Study Design

  • Randomization
  • Parallel

Patients with severe coronary artery calcium undergoing PCI were randomized to intravascular lithotripsy (n = 19) versus balloon angioplasty (n = 21).

Inclusion criteria:

  • Patients with severe coronary artery calcium undergoing PCI

Principal Findings:

The primary outcome, stent expansion, was 83.9% in the intravascular lithotripsy group vs. 82.2% in the balloon angioplasty group (p = 0.63).

Interpretation:

In this small trial, there was no difference in stent expansion with intravascular lithotripsy compared with balloon angioplasty in calcified coronary arteries. Larger trials are required to determine the impact of intravascular lithotripsy on clinical events.

References:

Presented by Dr. Maarten Vink at the Transcatheter Cardiovascular Therapeutics meeting (TCT 2022), Boston, MA, September 19, 2022.

Clinical Topics: Invasive Cardiovascular Angiography and Intervention, Noninvasive Imaging, Interventions and Imaging, Angiography, Nuclear Imaging

Keywords: Angioplasty, Balloon, Coronary, Coronary Angiography, Dilatation, Lithotripsy, Percutaneous Coronary Intervention, Stents, TCT22, Transcatheter Cardiovascular Therapeutics, Vascular Calcification


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