Development and Validation of a Short Version of the Seattle Angina Questionnaire
What is the validity of the shortened version of the Seattle Angina Questionnaire (SAQ-7) and its summary score, including its psychometric (validity, reliability, and responsiveness to change) and prognostic properties?
Using data from 10,408 patients with coronary artery disease (CAD) from five multicenter registries, the investigators derived and validated a shortened version of the SAQ (SAQ-7) among patients presenting with stable CAD, undergoing percutaneous coronary intervention (PCI), and after acute myocardial infarction. The authors examined the psychometric properties of the SAQ-7 as compared with the full SAQ.
Seven items from the Physical Limitation, Angina Frequency, and Quality of Life domains were identified for the SAQ-7, with high levels of concordance (0.88–1.00) with each original SAQ domain. The SAQ-7 demonstrated good construct validity (compared with Canadian Cardiovascular Society class for angina), with a correlation of 0.62 and 0.38 for patients with stable CAD and undergoing PCI, respectively. It was highly reproducible in patients with stable CAD (intraclass correlation, ≥0.78) and exhibited excellent responsiveness in patients after PCI (≥18 points in each SAQ domain). Finally, the SAQ-7 was predictive of 1-year mortality and readmission.
The authors concluded that they have validated a shortened 7-item SAQ instrument for use in clinical trials and routine care.
The study investigators derived and validated a 7-item shortened version of the SAQ (SAQ-7), as well as an overall summary score, to facilitate assessments of health status in patients with CAD. The SAQ-7 performed well in patients with stable CAD, undergoing PCI, and presenting with acute myocardial infarction. The SAQ-7 has the potential to improve clinical care by providing physicians with an objective, efficient mechanism to follow the trajectory of their CAD patients’ health status.
Clinical Topics: Invasive Cardiovascular Angiography and Intervention
Keywords: Myocardial Infarction, Psychometrics, Quality of Life, Questionnaires, Health Status, Percutaneous Coronary Intervention
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