One Spouse with Heart Disease May Double Risk for Other

Lifestyle factors, caregiver stress thought to play a role in increased risk

Contact: Nicole Napoli,, 202-669-1465

WASHINGTON (May 05, 2021) -

Individuals living with a spouse with heart disease were more than twice as likely to have heart disease themselves, according to a study being presented at the American College of Cardiology’s 70th Annual Scientific Session.

Researchers surveyed more than 5,000 heterosexual couples over the age of 45 living in seven regions of China from 2014-2016. Participants provided information about their personal health history and that of their spouse, including details about risk factors such as body mass index and blood pressure; lifestyle factors such as physical activity, smoking and alcohol use; and socioeconomic factors. For the study, a history of cardiovascular disease was defined as experiencing a heart attack or stroke or having percutaneous coronary intervention or coronary artery bypass graft, which are procedures to open or bypass blocked arteries.

“We found that an individual’s cardiovascular disease risk is associated with the health status and lifestyle of their wife or husband,” said Chi Wang, MPH, a research fellow at Heart Health Research Center in Beijing and the study’s lead author. “In addition to sharing lifestyle factors and socioeconomic environment, our study suggests the stress of caring for a spouse with cardiovascular disease may contribute to increased cardiovascular risk.”

Previous research in this area has pointed to increased risks among those caring for a spouse after a stroke. The new study has a larger study population than previous studies and more comprehensive information on health status, risk factors and lifestyle variables, according to researchers.

Because the data came from multiple regions of China representing a wide range of economic and cultural backgrounds, Wang said the results likely would be similar to trends in other middle-income countries around the world. She said the findings underscore the need for preventive care for spouses of individuals with cardiovascular disease.

“Family-centered health care plays an important role in chronic health care around the world,” Wang said. “Our finding indicates caregivers’ health should be monitored as well as that of their spouse in the community and primary care setting.”

According to the findings, the relationship between a spouse’s history of heart disease and a person’s own risk was especially pronounced in men. Among men whose wives had heart disease, 28% had cardiovascular disease themselves, compared to 12.8% of men whose wives did not have heart disease. A man’s likelihood of cardiovascular disease was highest if his wife had a history of stroke, obesity or smoking. The researchers said the prominent role of women in determining a family’s diet could help explain the findings.

Among women whose husbands had heart disease, 21% had cardiovascular disease themselves, compared to just 9% of women whose husbands did not have cardiovascular disease. A woman’s likelihood of cardiovascular disease was highest if her husband had a history of stroke.

“The health status and risk factors of women, who are the drivers of lifestyle in a majority of families in different cultural backgrounds, seem to affect their husbands to a greater extent than husbands’ risk factors affect wives,” Wang said.

The researchers also examined diabetes trends but found that having a spouse with diabetes did not significantly increase a person’s own diabetes risk. This finding could indicate that genetic factors and family history of diabetes are the dominant factor for diabetes risk, Wang said.

For resources on being a caregiver for a heart disease patient, visit

Wang will present the study, “Association of Spousal Health Status and Cardiometabolic Risk Factors with Cardiovascular Disease and Diabetes Mellitus in China,” on Monday, May 17, at 12 p.m. ET / 16:00 UTC.

ACC.21 will take place May 15-17 virtually, bringing together cardiologists and cardiovascular specialists from around the world to share the newest discoveries in treatment and prevention. Follow @ACCinTouch, @ACCMediaCenter and #ACC21 for the latest news from the meeting.

The American College of Cardiology envisions a world where innovation and knowledge optimize cardiovascular care and outcomes. As the professional home for the entire cardiovascular care team, the mission of the College and its 54,000 members is to transform cardiovascular care and to improve heart health. The ACC bestows credentials upon cardiovascular professionals who meet stringent qualifications and leads in the formation of health policy, standards and guidelines. The College also provides professional medical education, disseminates cardiovascular research through its world-renowned JACC Journals, operates national registries to measure and improve care, and offers cardiovascular accreditation to hospitals and institutions. For more, visit


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