Navigating Recent Clinical Trial Results: Cardiovascular Risk Reduction in a Patient with Prior Ischemic Stroke

62 year-old female presents for follow-up in clinic.

PMH: HTN, type 2 diabetes, ischemic stroke (3 months ago)

aspirin 81 mg PO daily
atorvastatin 40 mg PO daily
lisinopril 40 mg PO daily
metformin 1000 mg PO twice daily

Vitals: BP: 143/88 mm Hg, P: 68 beats per minute, BMI 32 kg/m2
Labs: eGFR 65 mL/min/1.73m2, liver function normal, A1C: 8.1%

The patient states adherence with appropriate dietary habits.

During the clinician-patient discussion at today's visit, you express concern about the patient's high atherosclerotic cardiovascular disease risk. The patient states she is willing to take additional medications to lower her risk.

According to recent clinical trial evidence, which ONE of the following medications has been shown to reduce this patient's risk of stroke?

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