A Patient with Symptomatic Peripheral Artery Disease Undergoing Endovascular Intervention

A 61-year-old male complains about severe cramping calf pain after walking a few blocks, associated with mild rest pain. He also complains of a cold right lower limb and ipsilateral "odd prickling" sensation. His past medical history includes hypertension, diabetes, and dyslipidemia, which are treated appropriately. He smokes one pack/day for the last 15 years. His vital signs are normal, except for a slightly increased blood pressure. He has palpable pulses throughout. His left lower limb and foot are well perfused and warm, while the right foot is cold and pale. No pain is elicited during passive movement of his legs, relatively to his hips. His resting ankle-branchial index (ABI) is 0.8 and it does not change after exercise. Neurological examination is normal. The patient was admitted to the hospital for imaging and further evaluation. De novo infrainguinal atherosclerotic lesions in the right superficial femoral artery were identified and treated endovascularly with primary stenting.

Which of the following listed drugs/drug combinations would be the most appropriate, chronic therapeutic approach after endovascular intervention in order to reduce major cardiovascular and adverse limb ischemic events?

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