It is uncommon for patients to have type 2 diabetes without other cardio-renal-metabolic (CaReMe) conditions, according to research presented during the American Diabetes Association Scientific Sessions in San Diego, CA. As such, there is a "clinical need for novel type 2 diabetes treatment strategies that address both glycemia and coexisting disease states in this high-risk patient group," say study authors Robert J. LoCasale, MD, et al.

The cross-sectional study used data from the Diabetes Collaborative Registry between Jan. 1, 2013 and June 30, 2016. A total of 530,747 patients aged 18 years or older with type 2 diabetes were eligible for inclusion in the study. Patients with type 1 diabetes were excluded.

Results found that most patients (95.7 percent) had at least one other CaReMe condition in addition to type 2 diabetes, with the most prevalent being hypertension, hyperlipidemia, coronary artery disease and chronic kidney disease. More than half of patients (58.6 percent) had at least three additional CaReMe conditions. Study authors noted trends towards greater numbers of additional CaReMe conditions as median age, proportion of men and tobacco use increased. There was no clear relationship between body mass index and the number of additional CaReMe conditions.

The Diabetes Collaborative Registry is the first U.S. cross-specialty diabetes registry, designed to track and improve the quality of care of patients with diabetes and metabolic disease across primary and secondary care settings. To date the prevalence of CaReMe conditions have not been well described in a contemporary cohort of patients with type 2 diabetes. These findings contribute important evidence to these discussions. Additionally, study authors say the "overall cardiovascular risk of patients with different combinations of CaReMe conditions requires further exploration."

Keywords: Blood Glucose, Cardiovascular Diseases, Coronary Artery Disease, Cross-Sectional Studies, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Hyperlipidemias, Hypertension, Prevalence, Registries, Renal Insufficiency, Chronic, Risk Factors, Secondary Care, Tobacco Use, National Cardiovascular Data Registries, Diabetes Collaborative Registry, Diabetes Collaborative Registry, Metabolic Syndrome

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