Cutting Balloon to Optimize Predilatation for Stenting - COPS

Sep 26, 2022
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Author/Summarized by Author:
Anthony A. Bavry, MD, MPH, FACC
Summary Reviewer:
Deepak L. Bhatt, MD, MPH, MBA, FACC
Date Presented:
09/19/2022
Date Updated:
09/26/2022
Original Posted Date:
09/26/2022
References

Contribution To Literature:

The COPS trial found that cutting balloon angioplasty was associated with larger stent area versus noncompliant balloon angioplasty in calcified coronary lesions.

Description:

The goal of the trial was to evaluate cutting balloon angioplasty compared with noncompliant balloon angioplasty among patients with severe coronary artery calcium undergoing percutaneous coronary intervention (PCI).

Study Design

  • Randomization
  • Parallel

Patients with severe coronary artery calcium undergoing PCI were randomized to cutting balloon angioplasty versus noncompliant balloon angioplasty.

Inclusion criteria:

  • Patients with severe coronary artery calcium undergoing PCI

Principal Findings:

The primary outcome, minimum stent area at calcium site, was 8.2 mm2 in the cutting balloon group vs. 7.3 mm2 in the noncompliant balloon angioplasty group (p = 0.035).

Secondary outcomes:

  • Device failure rate: 6.8% in the cutting balloon group vs. 0% in the noncompliant balloon angioplasty group (p = 0.52)

Interpretation:

In this small trial, cutting balloon angioplasty was associated with larger minimal stent area compared with noncompliant balloon angioplasty in calcified coronary arteries. Larger trials are required to determine the impact of cutting balloon angioplasty on clinical events and how this technology compares alongside of atherectomy techniques.

References:

Presented by Dr. Antonio Mangieri at the Transcatheter Cardiovascular Therapeutics meeting (TCT 2022), Boston, MA, September 19, 2022.

Clinical Topics: Cardiac Surgery, Invasive Cardiovascular Angiography and Intervention, Aortic Surgery

Keywords: Angioplasty, Balloon, Coronary, Atherectomy, Coronary, Dilatation, Equipment Failure, Percutaneous Coronary Intervention, Stents, TCT22, Transcatheter Cardiovascular Therapeutics, Vascular Calcification


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