Atrial Fibrillation in Congenital Heart Disease
How do the types and patterns of atrial arrhythmias associated with congenital heart disease (CHD) vary with age?
This was a multicenter retrospective cohort study of patients from 12 centers across North America with heterogeneous forms of CHD born before 2003 and documented sustained atrial tachyarrhythmias including atrial fibrillation (AF).
The study’s important findings were that: 1) intra-atrial reentry tachycardia (IART) is the most common type of atrial arrhythmia in CHD affecting up to 62%, and its prevalence increases as the complexity of CHD increases. 2) AF increases with age and is the most common atrial arrhythmia in CHD patients over 50 years old. 3) The prevalence of permanent arrhythmias increases with age, affecting up to 20% of those over 50 years. A multivariable analysis revealed that older age, hypertension, and history of atrial septal defect independently increases the risk of AF. A history of fewer heart operations decreased the risk of AF.
The prevalence and pattern of atrial arrhythmias evolves with patient age. IART is the most common arrhythmia overall, but AF and permanent arrhythmias become increasingly problematic in older patients.
Atrial arrhythmias are a well-established, chronic problem in the adult CHD patient. This study further clarifies that problem and adds the unfortunate detail that permanent arrhythmias and AF become more common as these patients age. The growing population of CHD survivors means that atrial arrhythmias will remain a substantial problem that will require the collaborative efforts of adult and pediatric electrophysiology experts to manage.
Clinical Topics: Arrhythmias and Clinical EP, Cardiac Surgery, Congenital Heart Disease and Pediatric Cardiology, Invasive Cardiovascular Angiography and Intervention, Prevention, Implantable Devices, SCD/Ventricular Arrhythmias, Atrial Fibrillation/Supraventricular Arrhythmias, Cardiac Surgery and Arrhythmias, Cardiac Surgery and CHD and Pediatrics, Congenital Heart Disease, CHD and Pediatrics and Arrhythmias, CHD and Pediatrics and Interventions, CHD and Pediatrics and Prevention, CHD and Pediatrics and Quality Improvement, Interventions and Structural Heart Disease, Hypertension
Keywords: Arrhythmias, Cardiac, Atrial Fibrillation, Cardiac Surgical Procedures, Electrophysiology, Heart Defects, Congenital, Heart Septal Defects, Atrial, Hypertension, Risk, Secondary Prevention, Tachycardia
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