Cardiovascular Care for Pregnant Women With CVD
Quick Takes
- Cardio-obstetrics programs involve team-based care involving multidisciplinary collaboration among specialists in cardiology, maternal fetal medicine, anesthesiology, and other disciplines.
- Cardio-obstetrics programs may help reduce maternal morbidity and mortality, but prospective multicenter studies are needed.
Study Questions:
What are the clinical characteristics, maternal and fetal outcomes, and cardiovascular readmissions in a cohort of pregnant women with cardiovascular disease (CVD) followed by a cardio-obstetrics team?
Methods:
Data were analyzed from patients evaluated by a cardio-obstetrics team (January 1, 2010–December 31, 2019) at a quaternary care hospital in New York City. Data included demographics, comorbidities, underlying CVD, medications, maternal and fetal outcomes, and cardiovascular readmissions. A Cardiac Disease in Pregnancy (CARPREG) II score was calculated for each patient.
Results:
Of 306 pregnant women, mean age was 29 years, 52.9% were Hispanic or Latino, and 74.2% were insured through Medicaid. Forms of CVD included arrhythmia (28.8%), congenital heart disease (23.5%), and cardiomyopathy (23.5%). The median CARPREG II score was 3, and 42.5% had a score of 4 or higher. In this cohort, 11.4% had gestational diabetes, 9.5% had gestational hypertension, and 12.1% had pre-eclampsia. During delivery, 8.8% were admitted to the intensive care unit. Live births occurred in 98% of pregnancies with a mean gestational age of 38 weeks. One maternal death occurred in a woman with Eisenmenger syndrome. The 30-day readmission rate after delivery was 2% and median follow-up was 2.6 years.
Conclusions:
The authors concluded that this population of primarily Medicaid-insured women followed by a cardio-obstetrics team had favorable maternal outcomes and low rates of readmission. Prospective studies of cardio-obstetric models of care are still needed.
Perspective:
This study describes a population of patients managed by a cardio-obstetrics team at a quaternary hospital in New York City. The need for specialized cardio-obstetrics programs has arisen from increasing awareness of rising maternal mortality in the United States. CVD is now the leading cause of pregnancy-related deaths. Additionally, maternal mortality review committees have determined that many CVD-related deaths are preventable. Cardio-obstetrics teams involve multidisciplinary collaboration among cardiologists, obstetricians, maternal fetal medicine doctors, anesthesiologists, pharmacists, social workers, nurses, and others. In this study, the most common underlying cardiac conditions among pregnant patients were arrhythmias, cardiomyopathies, congenital heart disease, and valve disorders. Although the overall cohort had favorable maternal outcomes and low rates of readmission, there may be vast differences in risk among individual patients depending on the severity of the underlying CVD. Whether some women were counseled to not become pregnant is unknown. More research is needed about the management and outcomes of specific cardiac conditions during pregnancy. Multicenter collaboration among several cardio-obstetrics programs would allow for larger sample sizes of specific types of CVD during pregnancy. The Registry of Pregnancy and Cardiac disease (ROPAC) from the European Society of Cardiology has been informative, and additional efforts are underway for a pregnancy and heart disease registry in the United States. With more collaboration and larger data sets, we will be able to determine variations in management and outcomes for different populations and disease types.
Clinical Topics: Arrhythmias and Clinical EP, Cardiovascular Care Team, Congenital Heart Disease and Pediatric Cardiology, Diabetes and Cardiometabolic Disease, Heart Failure and Cardiomyopathies, Prevention, Vascular Medicine, Implantable Devices, SCD/Ventricular Arrhythmias, Atrial Fibrillation/Supraventricular Arrhythmias, Congenital Heart Disease, CHD and Pediatrics and Arrhythmias, CHD and Pediatrics and Prevention, Hypertension
Keywords: Anesthesiology, Arrhythmias, Cardiac, Cardiomyopathies, Diabetes, Gestational, Eisenmenger Complex, Female, Heart Defects, Congenital, Hypertension, Pregnancy-Induced, Maternal Mortality, Medicaid, Obstetrics, Pre-Eclampsia, Pregnancy, Pregnant Women, Primary Prevention
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