Journal Wrap | Renal Function Change and Post M-TEER Survival; Pregnancy Biomarkers and CV Risk; More

The hottest research from various peer-reviewed journals – handpicked weekly by the ACC.

Renal Function Change and Survival Post Mitral TEER

In patients who underwent mitral transcatheter edge-to-edge repair (M-TEER), a >10% change in estimated glomerular filtration rate (eGFR) was associated with differences in survival at one year, according to study using data from the STS/ACC TVT Registry published in Structural Heart.

GLP-1s Reduce HF Hospitalizations vs. DPP-4s, Comparable to SGLT-2s

In patients with type 2 diabetes (T2D), the risk of hospitalization for heart failure (HHF) was significantly lower with GLP-1s than DPP-4 inhibitors while it was similar compared with SGLT-2 inhibitors, according to results from real-world emulation trials published in Circulation.

Third-Trimester Pregnancy Biomarkers and Greater CV Risk

Higher concentrations in the third trimester of the pregnancy-specific biomarker soluble fms-like tyrosine kinase-1 (sFlt-1) and the cardiovascular-specific biomarker high-sensitivity cardiac troponin I (hs-cTnI) were independently associated with subsequent cardiovascular disease, according to research published in JAMA Cardiology, suggesting that pregnancy may be a unique and important opportunity for cardiovascular risk assessment.

Differential Impact of ADT Drugs in Prostate Cancer on Coronary Plaque

In men with localized prostate cancer (PCa) treated with radiation and androgen-deprivation therapy (ADT), treatment with the gonadotropin-releasing hormone (GnRH) leuprolide, vs. relugolix, was associated with a significant 12-month increase in coronary artery plaque volume, according to a brief report of the REVELUTION trial published in JAMA.

Resources

Clinical Topics: Diabetes and Cardiometabolic Disease, Dyslipidemia, Heart Failure and Cardiomyopathies, Prevention, Vascular Medicine, Atherosclerotic Disease (CAD/PAD), Nonstatins, Novel Agents, Statins, Acute Heart Failure, Hypertension

Keywords: Cardiology Magazine, ACC Publications, CM-Apr-2026, National Cardiovascular Data Registries, STS/ACC TVT Registry, Registries, Glomerular Filtration Rate, Shock, Cardiogenic, Kidney Failure, Chronic, Heart Failure, Sodium-Glucose Transporter 2 Inhibitors, Diabetes Mellitus, Type 2, Glucagon-Like Peptide-1 Receptor, Dipeptidyl-Peptidase IV Inhibitors, Metabolic Diseases, Pregnancy Trimester, Third, Pregnancy Outcome, Pregnancy, Hypertension, Pregnancy-Induced, Gynecology, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Vascular Endothelial Growth Factor Receptor-1, Androgen Antagonists, Coronary Artery Disease, Leuprolide