Journal Wrap | HCM Risk Stratification; Single Pill Combo Cuts BP, Stroke

The hottest research from various peer-reviewed journals – handpicked weekly by the ACC.

Similar 10-Year Mortality With PCI, CABG in Unprotected LM CAD

In patients with unprotected left main (LM) coronary artery disease (CAD) and no additional complex lesions, the rate of all-cause mortality at 10 years was similar with PCI and CABG, according to the NOBLE study published in The Lancet.

Single Pill Combo Therapy Cuts BP, Recurrent Stroke Post ICH

A single pill combining three low-dose antihypertensive drugs added to standard care was associated with a lower incidence of recurrent stroke and major cardiovascular events, and improvement in blood pressure (BP), among patients with prior intracerebral hemorrhage (ICH), according to results of the TRIDENT trial published in NEJM.

Cardiac Measure Compliance Boosts Outcomes

Practice-level compliance with the heart failure (HF) composite measure as well as individual measures related to beta-blocker and ACE inhibitor/ARB use were associated with decreased risk of death or hospitalization, according to a study published in American Heart Journal.

CMR and NT proBNP Sharpen HCM Risk Stratification

Results from a prospective study using data from the National Heart, Lung, and Blood Institute's Hypertrophic Cardiomyopathy (HCM) Registry provide important evidence in support of incorporating cardiac magnetic resonance (CMR) imaging and NT-proBNP into the evaluation of risk in patients with HCM.

Resources

Clinical Topics: Cardiac Surgery, Cardiovascular Care Team, Heart Failure and Cardiomyopathies, Invasive Cardiovascular Angiography and Intervention, Noninvasive Imaging, Prevention, Atherosclerotic Disease (CAD/PAD), Aortic Surgery, Cardiac Surgery and Heart Failure, Acute Heart Failure, Heart Failure and Cardiac Biomarkers, Interventions and Coronary Artery Disease, Interventions and Imaging, Interventions and Structural Heart Disease, Hypertension

Keywords: Cardiology Magazine, ACC Publications, CM-Jun-2026, Coronary Artery Bypass, Coronary Artery Disease, Natriuretic Peptide, Brain, Cardiac Imaging Techniques, Cardiomyopathy, Hypertrophic, Antihypertensive Agents, Neurology, Blood Pressure, Stroke, Mortality, PINNACLE Registry, Angiotensin Receptor Antagonists, National Cardiovascular Data Registries, Ambulatory Care, Heart Failure, Hypertension