Covering top Late-Breaking Clinical Trials from Day 1 of ACC.22, JACC Editor-in-Chief Valentin Fuster, MD, PhD, MACC, is joined by Biykem Bozkurt MD, PhD, FACC; Joanna Chikwe, MD, FACC; Paul L. Douglass, MD, MACC; and Viviany R Taqueti, MD, MPH, FACC, in a trial-by-trial breakdown of the day’s most influential late-breaking science, including:

• VALOR-HCM: Mavacamten as An Alternative to Surgical Septal Myectomy or Alcohol Ablation in Patients With Severely Symptomatic Obstructive Hypertrophic Cardiomyopathy
• SODIUM-HF: Study of Dietary Intervention Under 100 Mmol in Heart Failure
• POISE-3: Efficacy and Safety of Tranexamic Acid in Patients Undergoing Noncardiac Surgery

A long-standing resource for busy cardiovascular professionals, ACC Cardiology Hour provides expert analysis and key takeaways on top clinical trials released during cardiology's biggest meetings. Visit JACC.org/CardiologyHour for more information.

Clinical Topics: Acute Coronary Syndromes, Anticoagulation Management, Arrhythmias and Clinical EP, Atherosclerotic Disease (CAD/PAD), Cardiac Surgery, Cardio-Oncology, Congenital Heart Disease and Pediatric Cardiology, Dyslipidemia, Geriatric Cardiology, Heart Failure and Cardiomyopathies, Invasive Cardiovascular Angiography and Intervention, Noninvasive Imaging, Pericardial Disease, Prevention, Pulmonary Hypertension and Venous Thromboembolism, Sports and Exercise Cardiology, Stable Ischemic Heart Disease, Valvular Heart Disease, Vascular Medicine

Keywords: ACC Annual Scientific Session, ACC22

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