Journal Wrap | Safety and Efficacy of Obicetrapib; Colchicine in Vascular Disease

The hottest research from various peer-reviewed journals – handpicked weekly by the ACC.

How Do Cardiometabolic Risk Factors in Pregnancy, Early Childhood Food Insecurity Impact Future CV Health?

Research examining how cardiometabolic risk factors in pregnant women may affect the blood pressure (BP) of their offspring and the association between early childhood food insecurity and future cardiovascular health were published in JAMA Network Open and in JAMA Cardiology, respectively.

TANDEM and BROADWAY: Investigating the Safety and Efficacy of Obicetrapib

A fixed-dose combination (FDC) therapy of obicetrapib plus ezetimibe was found to significantly reduce LDL-C in patients with preexisting or at high risk for developing atherosclerotic cardiovascular disease (ASCVD), according to results from the randomized, double-blind TANDEM trial published in The Lancet.

Colchicine vs. Placebo Reduces MACE in Patients With Vascular Disease

Colchicine substantially reduces major adverse cardiovascular events (MACE) including cardiovascular death, myocardial infarction (MI) and ischemic stroke compared with placebo in patients with vascular disease, according to two meta-analyses of randomized controlled trials (RCTs) published in the European Heart Journal.

DOACs vs. Warfarin After TAVR: Insights From the STS/ACC TVT Registry

Use of direct oral anticoagulants (DOACs) as opposed to warfarin after TAVR exhibited a lower risk of bleeding requiring hospitalization, all-cause mortality and stroke at one-year, according to a recent study published in the American Heart Journal.

Resources

Clinical Topics: Anticoagulation Management, Cardiac Surgery, Dyslipidemia, Invasive Cardiovascular Angiography and Intervention, Prevention, Cardiac Surgery and Arrhythmias, Lipid Metabolism, Nonstatins, Statins, Interventions and Vascular Medicine

Keywords: Cardiology Magazine, ACC Publications, Cardiometabolic Risk Factors, Food Insecurity, Blood Pressure, Pregnancy, Cholesterol, LDL, Cardiovascular Diseases, Ezetimibe, Ischemic Stroke, Colchicine, Atherosclerosis, Secondary Prevention, National Cardiovascular Data Registries, STS/ACC TVT Registry, Anticoagulants, Transcatheter Aortic Valve Replacement