The new ACC/AHA Guideline on the Management of Dyslipidemia offers a comprehensive "one-stop shop" for addressing the evaluation, management and monitoring of individuals with dyslipidemias, including high blood cholesterol, hypertriglyceridemia and elevated lipoprotein(a). The document consolidates evidence-based recommendations for managing dyslipidemias and retires and replaces the 2018 Guideline on the Management of Blood Cholesterol. Access the Hub.

New All-In-One App for Smarter CV Risk Assessment

The new CVD Risk Estimator Plus app launched just in time for ACC.26. The app replaces the ASCVD Risk Estimator Plus app and incorporates new AHA PREVENT™ equations that are central to both the new high blood pressure and dyslipidemia guidelines for more completely assessing and calculating cardiovascular risk. The app's built-in risk categories and exportable results help streamline clinician patient conversations and direct guideline aligned care. Download the app.

Additionally, a new ACC Scientific Statement outlines the rapidly evolving landscape of gene-editing therapies and their growing relevance to cardiovascular disease, offering clinicians an overview of both the promise and challenges of this transformative technology. Published in JACC, the statement highlights cardiovascular diseases that are currently most amenable to early application of gene editing, particularly monogenic disorders that can be modified through protein knockdown and whose pathogenic protein synthesis occurs in the liver. Read more.

To support clinicians caring for children with congenital heart defects (CHDs), the ACC has released new Concise Clinical Guidance (CCG) on the outpatient management of isolated left-to-right shunt lesions. These common defects, including atrial septal defect, ventricular septal defect, patent ductus arteriosus, and atrioventricular septal defect, are associated with significant variability in management, despite advances in treatment and improved outcomes. The document provides practical, expert-informed recommendations across surveillance, intervention, and post-intervention care, with a focus on echocardiography and electrocardiography in the outpatient setting. Read the complete CCG.

Clinical Topics: Congenital Heart Disease and Pediatric Cardiology, Congenital Heart Disease

Keywords: Cardiology Magazine, ACC Publications, CM-May-2026, Gene Editing, Dyslipidemia, Heart Defects, Congenital, American Heart Association