JACC in a Flash
Featured topics and Editors' Picks from all of ACC's JACC Journals.
Results from recent randomized placebo-controlled trials consistently indicate that renal denervation (RDN) provides significant reduction in ambulatory and office blood pressure (BP), regardless of whether or not an individual is on antihypertensive medications, according to research presented at TCT 2021. The findings, published in JACC: Cardiovascular Interventions, suggest that RDN could be a useful strategy within the broader spectrum of BP management.
A proof-of-concept experiment that integrates coronary CT scans and intracoronary imaging technologies within navigation systems could open the door to PCI with no contrast media or X-rays in humans, according to research presented at TCT 2021 and simultaneously published in JACC: Basic to Translational Science.
Left atrial appendage closure (LAAC) was noninferior to non-warfarin oral anticoagulants (NOAC) for major atrial fibrillation (AFib)-related cardiovascular or neurological events, based on prespecified long-term outcomes from the PRAGUE-17 trial presented at TCT 2021 and simultaneously published in the Journal of the American College of Cardiology. LAAC was also associated with less postprocedural bleeding.
Despite being at low risk for bleeding, nearly all patients on antiplatelet therapy developed gastrointestinal (GI) mucosal injury, according to findings from the OPT-PEACE trial presented during TCT 2021 and simultaneously published in the Journal of the American College of Cardiology. However, researchers noted that dual antiplatelet therapy (DAPT) for six months followed by six to 12 months of single antiplatelet therapy (SAPT) with aspirin or clopidogrel resulted in less gastrointestinal injury and clinical bleeding compared with a 12-month DAPT regimen.
Favorable 30-day safety and clinical outcomes were observed in patients with high surgical risk and moderate-severe/severe mitral regurgitation (MR) who were treated with the Intrepid transfemoral transcatheter mitral valve replacement (TMVR) system, according to early feasibility study results presented at TCT 2021 and simultaneously published in JACC: Cardiovascular Interventions.
Plaque rupture may be associated with more inflammation in the culprit plaque, culprit vessel and all three major coronary arteries vs. plaque erosion, according to a study evaluating pericoronary adipose tissue (PCAT) attenuation, an emerging marker of coronary inflammation. The findings were presented during AHA 2021 and published in JACC: Cardiovascular Imaging.
Risk-standardized 30-day mortality was lower for patients hospitalized with heart failure (HF) at safety-net hospitals (SNHs), as compared to non-safety-net hospitals (non-SNHs), but similar for stroke, and higher for acute myocardial infarction (AMI) between 2016 and 2019, according to a study that will be presented during AHA 2021 and published simultaneously in the Journal of the American College of Cardiology.
Keywords: ACC Publications, Cardiology Magazine, Acute Coronary Syndrome, Adipose Tissue, Administration, Oral, Aged, 80 and over, Angiography, Anticoagulants, Antihypertensive Agents, Aspirin, Atrial Appendage, Atrial Fibrillation, Blood Pressure, Boston, Capsule Endoscopy, Cardiologists, Cardiology, Carotid Arteries, Centers for Medicare and Medicaid Services, U.S., Clopidogrel, Computed Tomography Angiography, Confidence Intervals, Contrast Media, Coronary Vessels, Denervation, Diagnosis-Related Groups, Electric Impedance, Embolism, Emigration and Immigration, Family Characteristics, Feasibility Studies, Fee-for-Service Plans, Follow-Up Studies, Gastroenterologists, Heart Failure, Heart Septal Defects, Atrial, Hospitals, General, Hospitals, Teaching, Hypertension, Iatrogenic Disease, Incidence, Inflammation, Insurance Coverage, Intention to Treat Analysis, Ischemic Attack, Transient, Japan, Lipids, Macrophages, Medicare, Mitral Valve, Mitral Valve Insufficiency, Myocardial Infarction, Myocardial Ischemia, Outcome Assessment, Health Care, Ownership, Pacemaker, Artificial, Patient Discharge, Patient Protection and Affordable Care Act, Patient Readmission, Patient-Centered Care, Percutaneous Coronary Intervention, Pharmaceutical Preparations, Platelet Aggregation Inhibitors, Policy, Proof of Concept Study, Prospective Studies, Proton Pump Inhibitors, Quality of Life, Safety-net Providers, Stents, Sternotomy, Stroke, Tomography, Optical Coherence, Tomography, X-Ray Computed, Value-Based Purchasing, Ventricular Remodeling, X-Rays
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